Holarrhena antidysenterica in Inflammatory Bowel Disease: a potential review

Holarrhena antidysenterica belongs to the Apocynaceae family and is generally known as kurchi in Hindi. It a small deciduous tree found arid woods throughout world including India. H. Antidysenterica commonly used Indian traditional medicine treat Inflammatory Bowel disease, dysentery, diarrhoea worms intestines. Plant parts like bark are useful antimicrobial, anti-inflammatory analgesic treatments, amoebiasis, chronic bronchitis, boils, ulcers. The Phytoconstituents plant ergosterol, flavonoids, phenolic acids, resins, saponins, steroidal alkaloids, coumarins, tannins triterpenoids. Anti-amnesic, anti-diabetic, antibacterial action, anti-inflammatory, anti-diarrhoeal, antioxidant/free radical activity , scavenging, diuretic, anti-amoebic, anthelmintic anti-microbial effects pharmacological properties of antidysenterica. contains alkaloids most important which alkaloid conessine major therapeutic constituent. Conarrhimine, Conimine, Conamine, Conessidine, Isoconessimine, Dimethyl Conkurchine Holarrhimine among various studied. also includes gum, resin, tannin, lupeol digitenol glycoside Holadysone addition alkaloids. Bark malaria, chest infections, asthma, bronchopneumonia, stomach disorders, dyspepsia, dysentery.
 Keywords: HA- antidysenterica, IBD- Disease, Collitus